Pricing and Online Ordering at www.alphalabs.co.uk Pricing and Online Ordering at www.alphalabs.co.uk n freephone order 0800 387732 n buy online at www.alphalabs.co.uk nemail order sales@alphalabs.co.uk nfreefax order 0800 614249 4 5 Calprotectin Assays Calprotectin Sample Extraction Future-proof your Calprotectin Testing with BÜHLMANN: IBDoc®, Quantum Blue®, fCAL ELISA and fCAL turbo Elevated faecal calprotectin is a well proven biomarker for Inflammatory Bowel Disease (IBD) such as Ulcerative Colitis and Crohn’s Disease and can be used to easily and cost-effectively differentiate between these conditions and Irritable Bowel Syndrome (IBS). Since the publication of the NICE guidelines (DG11) in October 2013, supporting the use of calprotectin to differentiate between IBD and IBS, the level of calprotectin testing in UK laboratories has significantly increased: ■ As a screening test to help clinicians make informed decisions: ■ To monitor IBD positive patients to assist in better patient management - Predicting flares - Predicting post-operative relapse - Predicting response to therapy - Helping to keep patients in remission out of hospital Calprotectin can be used more extensively than just for an initial IBS/IBD screen test. Numerous publications suggest that regular monitoring of IBD patients can help to predict flares, response to therapy or post-operative relapse. Calprotectin concentrations can start to rise before the clinical symptoms become apparent, offering the opportunity for intervention therapy. Alpha Laboratories offers a wide range of calprotectin sample preparation and test formats, all from BÜHLMANN Laboratories AG. BÜHLMANN has specialised in calprotectin assays for 20 years and has the broadest range of faecal calprotectin assays available. These are scalable and flexible allowing hospitals to evolve their calprotectin service in line with changing demands. All the BÜHLMANN assays give quantitative measurements and are standardised together to give consistent results and cut-off values allowing for the smooth transition between assay technologies. For more information visit: www.calprotectin.co.uk Complete Range of Solutions for Calprotectin Testing <80µg/g Negative 80-160µg/g Retest in two weeks >160µg/g Positive Investigate for other causes of symptoms, e.g IBS, Food allergies Possible infection, NSAIDS, mild diverticulitis Refer for further evaluation To simplify and assist the preanalytical extraction of calprotectin from the stool samples the CALEX extraction device is available to minimise operator contact with the sample, whilst optimising extraction of calprotectin. Faecal Calprotectin Sample Extraction CALEX®Cap Calprotectin Stool Extraction Device CALEX® Cap is a stool extraction device providing rapid, clean and consistent sample preparation every time. The CALEX contains a measured amount of BÜHLMANN extraction buffer and is for exclusive use with all BÜHLMANN calprotectin assays. The CALEX extraction device improves laboratory workflow and efficiency by eliminating the need for sample weighing, pipetting or decanting and enables direct loading of the extraction device onto many ELISA processors and routine biochemistry analysers. Rapid, clean and consistent sample preparation is achieved every time. CALEX Cap Stool Extraction Device Product code Description Pack Size B-CALEX-C50 CALEX Cap Device 50 tubes B-CALEX-C200 CALEX Cap Device 200 tubes B-CALEX-C500 CALEX Cap Device 500 tubes B-CALEX-CCSET25 CE Marked CALEX Cap Collection Set 25 sets CALEX-CAL-CK020 UKCA Marked Faecal Calprotectin Collection Kit 20 kits CALEX-CAL-CK020P UKCA Marked Portal Delivery Calex Calprotectin Kit 20 kits AP0021 15.2mm Vacu-Re-Caps 1000 CALEX® Cap compared to manual extraction Passing-Bablok linear regression analysis: nEase of use for laboratory personnel and patients nDelivers a precise amount of faecal sample nOptimised sample dilution for maximum efficiency in stool extraction nApplication as a primary tube for many ELISA robots and routine biochemistry analysers n95kPa postal compliant nUN3373 and IATA 650 compliant for transport by air nModifications to the blue & white caps at either end enable them to be used on laboratory track systems for a truly automated workflow nCE and UKCA marked patient collection kits are available Vacu-Re-Caps can be used to quickly and cleanly reseal the CALEX after analysis. AP0021 Kaur. et al. Annals of Clinical Biochemistry 2020
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