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313 Neuroimmunology and Autoimmunity Autoantibody ELISA Assays Recent progress in the understanding of the clinical pathophysiology of autoimmune neuropathies has led to the increasing importance of measuring autoantibody concentrations. Anti-glycolipid autoantibodies have been implicated as potential pathogenetic agents in a number of peripheral neuropathies. The autoantibodies frequently react with epitopes of the carbohydrate region of cell surface glycoconjugates. The value of anti-glycolipid antibody assays for both diagnostic and research purposes (for the study of autoimmune peripheral neuropathies) is increasingly recognised. There is a significant correlation between particular clinical features and the species of anti-glycoconjugate antibodies in the serum. IgG antibodies are associated with acute neuropathies, whereas IgM classes are present in chronic conditions. A variety of peripheral neuropathies can be defined by their anti-glycolipid antibody profile. The specialist range of neuroimmunology ELISA kits from BÜHLMANN Laboratories provides a comprehensive tool box for this clinical and research area. Contents Page Autoantibodies 314 GanglioCombi ELISAs 315 Anti-MAG Autoantibody ELISA 315 Anti-SGPG Autoantibody ELISA 315 Anti-GM1 Autoantibody ELISA 315 Anti-C1q Autoantibody ELISA 316 Circulating Immune Complex ELISA 316 Anti-Interferon Autoantibody ELISA 317


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