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Pricing and Online Ordering at www.alphalabs.co.uk 296 Haemostasis Products listed on these pages are designed to offer laboratories a range of testing methods for Lupus Anticoagulant (LA) so that the recommendation to use, “Two or more tests … to screen for LA before the diagnosis is excluded” 1, can be met. 1. Brandt JT, Triplet DA, Alving B, Scherrer I, Criteria for the Diagnosis of Lupus. TEClot LA Screen Lupus Anticoagulant Testing dRVVT – screening reagents The TEClot LA Screen reagent is intended for qualitative determination of Lupus Anticoagulants (LAs) in human plasma. Russell’s viper venom directly activates Factor X to Factor Xa in the presence of phospholipid and calcium, leading to detectable clot formation in plasma. The TEClot LA Screen reagent is more sensitive for LAs than the APTT. The TEClot LA Screen reagent is intended to be used in conjunction with the TEClot Confirm reagent (ref. A0800-010 - see below). n Stable for 24 hours at 37C once reconstituted n Normal reference range: 25.6-41.8 seconds dRVVT – confirmation reagents CRYOcheck™ LA Sure TEClot LA Confirm n freephone order 0800 387732 n buy online at www.alphalabs.co.uk CRYOcheck™ LA Check A high phospholipid concentration that neutralizes LA, therefore, demonstrates the correction needed to confirm the presence of LA. n Easily adapted for use on most instruments n Unused reagent may be refrozen n 48-hour stability once thawed n Can be used in conjunction with CRYOcheck™ LA Check to confirm presence of LAs. n Manufactured to strict tolerances so screening and confirmation reagents do not need to be “matched” by specific lot numbers The reagent is designed to be used in conjunction with the TEClot LA Screen test (ref. A0700-020 - see above) to discriminate between LAs, factor deficiencies (II, V or X) or other inhibitors. If the clot time of the patient samples with the LA Screen procedure are greater than 3 standard deviations above the mean of the normal range and are not corrected by mixing studies, a lupus anticoagulant may be present. Under these circumstances, samples should be re-tested using the TEClot LA Confirm Reagent. The increased concentration of phospholipid is designed to neutralise LAs. n Stable for 24 hours at 37C once reconstituted n Normal reference range: 26.4-38.4 seconds A highly sensitive reagent that detects weak LA samples other test systems may miss. n Reagent contains Russell’s viper venom, phospholipids, and anti-heparin agents n Easily adapted for use on most instruments n Unused reagent may be refrozen n 48-hour stability once thawed n Ready to use in minutes CRYOcheck™ LA Check Catalogue Number Description Pack Size CHK25-10 LA Check 25 x 1ml CHK80-10 LA Check 80 x 1ml Precision Biologic TEClot LA Screen Catalogue Number Description Pack Size A0700-020 LA Screen Reagent 10 x 2ml TECO Medical CRYOcheck™ LA Sure Catalogue Number Description Pack Size SUR25-10 LA Sure 25 x 1ml Precision Biologic TEClot LA Confirm Catalogue Number Description Pack Size A0800-010 LA Confirm Reagent 10 x 1ml TECO Medical Lupus Anticoagulation Testing frozen plasma frozen plasma


Catalogue_WEB_WoP_Jun16
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