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Pricing and Online Ordering at www.alphalabs.co.uk Clinical Chemistry Topiramate Competitive immunoassay for quantification of topiramate in serum or plasma. Topiramate (also known as 2,3:4,5-Di-O-isopropylidene-beta- D-fructopyranose sulfamate) is an anti-convulsant drug used in monotheraray or as part of a multidrug regime for the management of epilepsy. Quantitative determination in serum or plasma can help aid Clinical decisions about drug dosage and epilepsy management. n Dual liquid-stable reagent n Range: 1.5-54.00µg/ml n Excellent correlation with FPIA method Technical information: Competitive immunoassay for quantification of topiramate in serum or plasma. Topiramate in the patient sample competes with glucose-6-phosphate dehydrogenase (G6PDH) labelled drug in reagent 2 to bind the antibody in reagent 1. Binding of the labelled topiramate reduces enzyme activity and therefore the rate of NAD to NADH conversion. Description Pack Size 5015-0001-00 Topiramate Assay 1x28ml;1x14ml 5015-0002-00 Topiramate Calibrator 1x4ml,5x2ml 5015-0003-00 Topiramate Controls 3x4ml ARK Diagnostics Valproic Acid Topiramate Catalogue Number Immunoturbidimetric assay for quantitative determination of valproic acid in human serum. Valproic acid is a popular drug used to control seizures in epileptic patients. Measuring circulating valproic acid can enable clinicians to establish the correct dosage for a patient and minimise toxicity. Monitoring can also provide clinicians with information when patients are failing to respond to therapy or when changes are being made to the medication regime. n Liquid-stable reagent, ready to use n Range: 10.46-157µg/ml n 6-point calibration curve Technical information: Latex particles coated with valproic acid are agglutinated when mixed with the valproic acid anti-body solution. Valproic acid in the patient sample competes with the latex particles slowing the process of agglutination. The absorbance change resulting from agglutination is inversely proportional to the amount of valproic acid in the patient sample. Valproic Acid Catalogue Number Description Pack Size A01420 Valproic Acid 2x12;2x5ml A12450 TDM Calibrator 6x3ml A09450 TDM Control Set 3x5ml DiaLab Phenobarbital For quantitative determination of phenobarbital in human serum. Phenobarbital is often used in the management of epilepsy but considerable variations in serum concentration are seen between patients receiving the same dose. Measuring circulating phenobarbital enable clinicians to establish the correct dosage for a patient and reduce the risk of drug toxicity. n Liquid-stable reagent, ready to use n Range: 2.9-87.7µg/ml n 6-point calibration curve Technical information: Latex particles coated with Phenobarbital are agglutinated when mixed with the Phenobarbital anti-body solution. Phenobarbital in the patient sample competes with the latex particles slowing the process of agglutination. The absorbance change resulting from agglutination is inversely proportional to the amount of Phenobarbital in the patient sample. Phenobarbital Catalogue Number Description Pack Size A03439 Phenbarbital Assay 2x17;2x6ml A12450 TDM Calibrator 6x3ml A09450 TDM Control Set 3x5ml DiaLab Phenytoin Immunoturbidimetric assay for quantitative determination of phenytoin in human serum. Phenytoin is used alone or in combination for the management of epilepsy. Monitoring of serum levels is recommended at the start of therapy to ensure the dose results in a circulating concentration within the therapeutic range. Monitoring can also assist clinical dosage decisions when there are changes to the medication regime – addition or removal of other drugs. n Dual liquid-stable reagent n Measuring range 1.1-40 µgl/ml n Manual and automated protocols Technical information: The Dialab Phenytoin method is a dual reagent system (R1:2x17ml; R2:2x6ml) with both reagents supplied ready to use. Latex particles coated with Phenytoin are agglutinated when mixed with the Phenytoin antibody solution. Phenytoin in the patient sample competes with the latex particles slowing the process of agglutination. The absorbance change resulting from agglutination is inversely proportional to the amount of Phenytoin in the patient sample. Phenytoin Catalogue Number Description Pack Size A03441 Phenytoin 2x17;2x6ml A12450 TDM Calibrator 6x3ml A09450 TDM Control Set 3x5ml DiaLab Clinical Chemistry - Therapeutic Drug Monitoring n email order sales@alphalabs.co.uk n freefax order 0800 614249 255


Catalogue_WEB_WoP_Jun16
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