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Pricing and Online Ordering at www.alphalabs.co.uk Clinical Chemistry Gamma-Hydroxybutyric Acid (GHB) The GHB assay has been designed for the direct and quantitative determination of GHB in human urine and serum. The assay can be adapted to clinical chemistry analysers according to specific instrument protocols. The GHB assay range is based on a standard enzymatic immunoassay. n Dual lyophilised reagents n Open-vial stability: Incubation buffer - until expiry date at 2-8C Cofactor, Enzyme, Calibrators and Controls - 60 days at 2-8C (Once reconstituted) n Dynamic range: 5-230mg/L Technical information: GHB + NAD+ Rec. Enzyme Product + NADH + H+ The GHB is converted to its metabolite, succinic semialdehyde (SSA), by the action of GHB-Dehydrogenase (Rec Enzyme) and oxidised nicotinamide adenine dinucleotide (NAD+). The increase in absorbance at 340nm resulting from the reduction of NAD+ into NADH is proportional to the amount of GHB in the sample. GHB Catalogue Number Description Pack Size KK-GHB GHB enzymatic assay 100 Tests BÜHLMANN Laboratories Glucose Enzymatic-colorimetric determination of glucose in serum, plasma and cerebrospinal fluid (CSF). Glucose is an important carbohydrate that is used as a source of energy for cellular functions. Measurement of glucose concentration in serum or plasma is mainly used in the diagnosis and treatment of diabetes mellitus. n Single liquid-stable reagent n Linearity: up to 400 mg/dL n On-board stability is typically 60 days Technical information: Glucose is oxidised by glucose oxidase (GOD) into gluconic acid and hydrogen peroxide, which, in presence of peroxidase (POD), reacts with 4-aminoantipyrine and hydroxybenzoic acid, forming a red compound. Colour intensity is proportional to the concentration of analyte in the sample. Glucose Catalogue Number Description Pack Size 17630H Glucose Liquid Colorimetric Assay 6x65ml 16550 Clin Chem Calibrator 4x3ml 16150 Clin Chem Control 1 6x5ml 16250 Clin Chem Control 2 6x5ml Sentinel Glucose-6-phosphate dehydrogenase (G6P-DH) Kinetic determination of G6P-DH activity in serum, plasma and erythrocytes. G6P-DH deficiency is the most common enzymopathy and is caused by familial mutations in the X chromosome. It can cause increased destruction of red cells and anaemia. n Triple reconstituted/liquid-stable reagent n Linearity: up to 50 U/L n Reconstituted reagent stability: 30 days when stored at 2-8C Technical information: G6P-DH catalyses the reaction of glucose-6-phosphate and NADP+ to gluconate-6-phosphate and NADPH+. The increase in absorbance due to the reduction of NADP+ is proportional to the activity of G6P-DH. G6P-DH Catalogue Number Description Pack Size 17005 G6P-DH Kinetic Assay 1x100;1x2;1x2ml Sentinel Glutamate Dehydrogenase (GLDH) For quantification of glutamate deyhdrogenase in serum or plasma The mitochondrial enzyme glutamate dehydrogenase (GLDH) is found in a number of tissues but serum GLDH originates predominately from hepatocytes in the liver. Since the mitochondria must be severely damaged for the GLDH to leak out of the cell, increased serum concentrations are indicative of liver damage. n Ready to use liquid reagents n Linearity: Up to 120 U/L n UV kinetic method in accordance with DGKC Technical information: 2-Oxoglutarate, ammonia ions and NADH is reversibly converted to L-Glutamate, NAD+ and water. The decreasing rate of rate of absorbance as a result of NADH oxidation is directly proportional to GLDH activity. Glutamate Dehydrogenase Catalogue Number Description Pack Size D03773 Glutamate Dehydrogenase Assay 5x50ml D98485SV Diacal Auto 1x3ml D98481SV Diacon Normal Control 1x5ml D98482SV Diacon Abnormal Control 1x5ml Dialab Clinical Chemistry - G n email order sales@alphalabs.co.uk n freefax order 0800 614249 237


Catalogue_WEB_WoP_Jun16
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