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Catalogue_WEB_WoP_Jun16

Clinical Chemistry C-reactive Protein CRP is recognised as one of the most sensitive acute phase proteins and is elevated in many diseases with a component of active inflammation or tissue destruction. Pricing and Online Ordering at www.alphalabs.co.uk n freephone order 0800 387732 n buy online at www.alphalabs.co.uk 234 Technical information: When a sample is mixed with the buffer solution containing antibody, CRP in the sample combines specifically with anti-human CRP antibodies bound to latex particles to yield an insoluble aggregate that causes increased turbidity. The degree of turbidity can be measured optically and is proportional to the amount of CRP present. CRP (Latex Turbidimetric) Catalogue Number Description Pack Size 462-39493 LT CRP HS11 R1 Buffer 2x40ml 468-39593 LT CRP HS11 R2 Latex 2x40ml 460-25801 LT CRP HS Calibrator 5x2ml Wako Chemicals CRP Ultrasensitive (Turbidimetric) For the quantitative immunoturbidimetric determination of CRP in serum and plasma: standard and ultrasensitive protocols. n Dual liquid-stable reagent n Measuring range: Standard Method: 0.1-320 mg/L Ultrasensitive Method: 0.05-160 mg/L n Open-vial stability: 60 days when stored at 2-8C Technical information: The determination is based on a turbidimetric reaction between a specific antiserum adsorbed onto latex particles and CRP. The change in absorbance caused by the immuno-complex is proportional to the concentration of the analyte in the sample. CRP Ultrasensitive (Turbidimetric) Catalogue Number Description Pack Size 11508H CRP Ultra Turbidimetric Assay 2x20;2x20ml 11508A CRP Ultra Turbidimetric Assay 3x50;3x50ml 11532 CRP Calibrator Set 7x2ml 11533 CRP Calibrator US* 1x2ml 11540 CRP Control US* 3x2ml 11211A Immuno Control Set (2 levels) 2x(2x1)ml Sentinel *For ultrasensitive method Creatine Kinase - MB (CK-MB) Kinetic determination of the CK-B isoenzymes (CK-MB and CK-BB) of CK in serum. CK catalyses the reversible phosphorylation of creatine by ATP. CK is a dimer composed of two subunits forming 3 active isoenzymes: BB (CK-1), MB (CK-2), MM (CK-3). CK-BB isoenzyme only rarely appears in serum. Elevated CK values are due to muscular damage and associated pathologies. CK-2 determination is used for the diagnosis and follow-up of AMI (acute myocardial infarction) and some muscular diseases. n Dual liquid-stable reagent n Linearity: up to 1000 U/L n On-board stability is typically 25 days Technical information: CK catalyses the reaction between creatine phosphate and ADP forming creatine and ATP. The ATP generated, in presence of glucose and hexokinase (HK), gives ADP and glucose-6-phosphate. The glucose-6- phosphate formed, in the presence of glucose-6-phosphate dehydrogenase (G6P-DH), reacts with NADP+ forming 6- phosphogluconate and NADPH. The presence of specific mouse antibodies that inhibit the CK-MM activity in the reaction mixture allows the determination of the residual activity of CK-B isoenzymes (CK-MB and CK-BB). The increase in absorbance due to the conversion of ß-NADP+ to ß-NADPH is used to measure the activity of CK-B. Creatine Kinase - MB (CK-MB) Catalogue Number Description Pack Size 17649H CK-MB Liquid Kinetic Assay 1x65ml;1x15ml 16299C CK-MB Calibrator 2x1ml 16299S CK-MB Control 2x1ml Sentinel CRP Reagent (Latex Turbidimetric) The CRP-HS reagent is a latex enhanced turbidimetric immunoassay. n Dual liquid-stable reagent n Measurable range: 1-350 mg/L n Standardised to ERM-DA470 Clinical Chemistry - CRP /Creatinine Kinase CRP Colour Enhanced Latex Agglutination Tests To overcome the challenge of reading grey latex colour enhanced latex makes the results much easier to visualise. With this method the agglutinates change colour and migrate to the periphery of the circle. In addition the background colour changes, enhancing the contrast between negative and positive results. n Kits come complete with disposable slides, sampling pipettes and controls n No sample dilution required n Enhanced readability Available in a range of packs size to suit varying workloads CRP (Latex Agglutination) Catalogue Number Description Pack Size CRC-50 C.Reactacol 50 tests CRC-100 C.Reactacol 100 tests Immunostics


Catalogue_WEB_WoP_Jun16
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