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Pricing and Online Ordering at www.alphalabs.co.uk Clinical Chemistry Ceruloplasmin (Turbidimetric) For the quantitative immunoturbidimetric determination of ceruloplasmin in serum and plasma. Ceruloplasmin determination is a diagnostic parameter in central nervous system diseases of obscure etiology. Low levels of ceruloplasmin occur in Menkes’ syndrome, nephritic syndromes and in some cases of advanced liver diseases. High levels of ceruloplasmin occur in a variety of neoplastic and inflammatory states. n Dual liquid-stable reagent n Measurable range: 5-90mg/dL n Suitable for both automated and manual methods n Open-vial stability: 120 days when stored at 2-8C Technical information: The determination is based on a turbidimetric reaction between a specific polyclonal antiserum and ceruloplasmin in the presence of polyethylenglycol polymer (PEG). The change in absorbance caused by the immuno-complex is proportional to the concentration of the analyte in the sample. Ceruloplasmin (Turbidimetric) Catalogue Number Description Pack Size 11065N Ceruloplasmin Turbidimetric Assay 2x50;1x8ml 11200D Plasmaproteins Cal 3x1ml 11211A Immuno Control Set (2 levels) 2x(2x1)ml Sentinel Cholesterol Enzymatic-colorimetric determination of cholesterol in serum and plasma. Total cholesterol level is one parameter used in determining the risk of developing coronary atherosclerosis. n Single liquid-stable reagent n Linearity: up to 70mg/dL n On-board stability is typically 60 days Technical information: Cholesterol is hydrolysed into free cholesterol and fatty acids by cholesterol esterase (CHE). The cholesterol is oxidised into cholestene-3-one and H2O2 in the reaction catalysed by cholesterol oxidase (CHOD). The peroxidase (POD) catalyses the reaction between H2O2, 4-aminoantipyrine (AP) and hydroxybenzoate to produce a red compound. The colour intensity of this compound is proportional to the total cholesterol present in the sample. Cholesterol Catalogue Number Description Pack Size 17644H Cholesterol Liquid Colorimetric Assay 6x65ml 16550 Clin Chem Calibrator 4x3ml 16150 Clin Chem Control I 6x5ml 16250 Clin Chem Control II 6x5ml Sentinel Cholesterol - High-Density Lipoprotein (HDL) For the determination of HDL cholesterol in serum. There is a strong negative relationship between the concentration of HDL cholesterol and coronary heart disease (CHD). HDL cholesterol is used as a predictive test for patients at risk of developing CHD. This reagent is intrinsically less susceptible to interference from icteric, lipaemic and haemolysed samples than reagents which use a detergent to remove LDL, VLDL & Chylomicrons. n Dual liquid reagent system n Linearity: Up to 180mg/dL n Open-vial stability: 60 days when stored at 2-10C Technical information: Anti-human β-lipoprotein antibody in Reagent 1 binds to lipoproteins (LDL, VLDL and chylomicrons) other than HDL. The antigen-antibody complexes formed block enzyme reactions when Reagent 2 is added. Cholesterol esterase (CHE) and cholesterol oxidase (CO) in Reagent 2 react only with HDL-C. Hydrogen peroxide produced by the enzyme reactions with HDL-C yields a blue colour complex upon oxidative condensation of F-DAOS (N-ethyl-N-(2-hydroxy-3-sulfopropyl)-3, 5-dimethoxy-4- fluoroaniline, sodium salt) and 4-aminoantipyrine (4-AA) in the presence of peroxidase (POD). By measuring the absorbance of the blue colour complex produced, at the optimum wavelength of 593nm, the HDL-C concentration in the sample can be calculated when compared with the absorbance of the HDL-C Calibrator. Cholesterol - HDL Catalogue Number Description Pack Size 412-72395 HDL-Cholesterol R1 Kit 4x60ml 412-72495 HDL-Cholesterol R2 Kit 4x20ml 418-72395 HDL-Cholesterol R1 Kit 4x270ml 418-72495 HDL-Cholesterol R2 Kit 4x90ml 416-51095 HDL-Cholesterol Calibrator 4x3ml Wako Chemicals Clinical Chemistry - Cholesterol n email order sales@alphalabs.co.uk n freefax order 0800 614249 231


Catalogue_WEB_WoP_Jun16
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