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Pricing and Online Ordering at www.alphalabs.co.uk Clinical Chemistry Bile Acids For the determination of total bile acid in serum or plasma. Raised levels in pregnancy are indicative of cholestasis. An increased level in fasting or postprandial state is considered a specific indicator of liver disease. Decreased levels indicate bile acid malabsorption. n Dual liquid-stable reagent n Linearity: up to 180 μmol/L n Open-vial stability: 4 weeks when stored at 2-8C Technical information: bile acids + Thio-NAD Oxid. bile acids + Thio-NADH Oxid. bile acids + NADH bile acids + NAD 3-α-Hydroxysteroid dehydrogenase (3-α-HSD) oxidises bile acids to 3-keto steroids, whereby Thio-NAD is reduced to Thio-NADH. The reaction is reversible and the same enzyme can convert 3-keto steroids and NADH to bile acids and NAD (recycling of bile acids). The rate of formation of the Thio-NADH is determined by measuring change of absorbance at 405 nm. Expected Values: 0 -10μmol/L in serum or plasma Sensitivity: Lower limit of linearity is 1μmol/L Bile Acids Catalogue Number 3-α-HSD 3-α-HSD Description Pack Size 903120 Total Bile Acids Assay R1: 4x22.5ml, R2: 1x30ml 903115 Total Bile Acids Assay R1: 4x45ml, R2: 1x60ml 903210 Bile Acid Standard 1x5ml D98481SV Diacon Normal Control 1x5ml D98482SV Diacon Abnormal Control 1x5ml Dialab Bilirubin Serum bilirubin measurement is widely used as a screening test for liver functions. Total bilirubin is the sum of the unconjugated and conjugated fractions, and is elevated in conditions causing obstruction of the bile duct, hepatitis, cirrhosis, in haemolytic disorders and several inherited enzyme deficiencies. Indirect bilirubin is elevated by pre-hepatic causes such as haemolytic disorders or liver diseases resulting in impaired entry, transport or conjugation within the liver. The vanadate oxidation method for measuring serum bilirubin shows good correlation with the Acid Diazo method but has advantages in terms of low signal interference by co-existent serum substances such as haemoglobin and an extended stability in liquid form. n Dual liquid-stable reagent n Measuring range: Direct: 0.1-20mg/dL Total: 0.1-40mg/dL n Open-vial stability: 4 weeks when stored at 2-8C Bilirubin Catalogue No. Description Pack Size 411-23695 Direct Bilirubin L-Type R1 Assay 4x70ml 413-23895 Direct Bilirubin L-Type R2 Assay 4x18ml 417-23295 Total Bilirubin L-Type R1 Assay 4x70ml 419-23495 Total Bilirubin L-Type R2 Assay 4x18ml 419-73295 Bilirubin Calculator 4x3ml Wako Chemicals Calcium Direct colorimetric determination of calcium in serum, plasma and urine. Calcium plays an essential role in many cell functions: muscle contraction, bone mineralisation and transmission of nerve impulses. Calcium measurement in blood is useful in the follow-up of patients with osteoporosis or kidney diseases and in the diagnostic of malignant diseases. n Dual liquid-stable reagent n Linearity: up to 20 mg/dL n Open-vial stability: 90 days when stored at 2-8C n Includes standard Technical information: Cresolphtalein Complexone (CPC) reacts with calcium ions at pH > 10 to form a red coloured complex, the intensity of which is directly proportional to the concentration of calcium in the sample. Calcium Catalogue Number Description Pack Size 17667H Calcium Liquid Colorimetric Reagent 3x55ml;1x50ml 16550 Clin Chem Calibrator 4x3ml 16150 Clin Chem Control 1 6x5ml 16250 Clin Chem Control 1 6x5ml Sentinel Clinical Chemistry - Bile Acids/Bilirubin n email order sales@alphalabs.co.uk n freefax order 0800 614249 227


Catalogue_WEB_WoP_Jun16
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