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Clinical Chemistry Beta-2 Microglobulin Apoliproteins (Turbidimetric) Pricing and Online Ordering at www.alphalabs.co.uk n freephone order 0800 387732 n buy online at www.alphalabs.co.uk 226 Aspartate Aminotransferase (AST) Kinetic determination of AST according to IFCC recommendations in serum and plasma. ALT and AST are enzymes which catalyse the conversion of -keto acids into amino acids by transfer of amino groups. AST is a cytoplasmic and mitochondrial enzyme; increased AST levels may indicate myocardial infarction, muscle dystrophy or organ damage. n Dual liquid-stable reagent n Linearity: up to 300 U/L n On-board stability is typically 30 days Technical information: AST catalyses the reaction of transamination between -ketoglutaric acid and L-aspartic acid, with formation of L-glutamic acid and oxalacetic acid. The formed oxalacetic acid, in presence of malate dehydrogenase (MDH), reacts with ß-NADH2 by forming lactic acid and ß-NAD in the same quantity. By measuring the variation of absorbance caused by ß-NAD in an interval of time, the enzyme activity in the sample can be calculated. Aspartate Aminotransferase (AST) Catalogue Number Description Pack Size 17224H AST UV Liquid 6x80;4x21ml 16550 Clin Chem Calibrator 4x3ml 16150 Clin Chem Control 1 6x5ml 16250 Clin Chem Control 1 6x5ml Sentinel For quantitative immunoturbidimetric determination of ß-2 Microglobulin in human serum or urine. ß-2 Microglobulin is a protein found on the cell membrane. Free ß-2 microglobulin is the result of cell breakdown. It is secreted by renal glomeruli and absorbed and catabolised by the renal tubular cells. Decreased glomerular filtration is associated with high serum levels of ß-2 microglobulin. Conversely, tubular insufficiency is associated with a normal serum level but elevated urine levels. High serum levels may also been seen in acute leukaemia. n Latex immunoturbidimetric assay n Measuring range: 0-11 mg/L n No hook effect Technical information: This is an immunoturbidimetric assay based on the formation of an insoluble complex between beta-2 microglobulin in the patient sample and the anti-beta- 2 microglobulin coated latex. Beta-2 Microglobulin Catalogue Number Description Pack Size A00511 Beta-2 Microglobulin Turbidimetric Reagent 1x10ml;5x25ml A00735 Beta-2 Microglobulin Turbidimetric Reagent 4x1ml A00818 Beta-2 Microglobulin Control 1x1ml A00590 Protein Control 1x1ml A08591 Protein Control Low 1x1ml Dialab For quantitative determination of Apolipoproteins in serum or plasma. Apolipoprotein A1 is a major component of high-density lipoprotein (HDL). It enhances the solubilisation of HDL Cholesterol and activates lecithin cholesterol acyltransferase (LCAT). Low levels are associated with atherosclerosis. Apolipoprotein B is contained in low-density lipoproteins (LDL). It is directly related to transport of cholesterol or triglyceride and is known as a virulent factor in atherosclerotic disorders. n Dual buffer with antibody preparation n Measuring range: - Apolipoprotein A1: 30-270 mg/dL - Apolipoprotein B: 40-800 mg/dL n Open-vial stability: 60 days when stored at 2-8C Technical information: Apolipoprotein in the sample combines with a specific antibody to yield an insoluble aggregate that causes turbidity. The degree of turbidity can be measured optically and is proportional to level of analyte in the sample. Apoliprotein (Turbidimetric) Catalogue Number Description Pack Size 11040N APO A-1 Turbidimetric Reagent 2x50ml,2x1ml,1x10ml 11042N APO B Turbidimetric Reagent 2x50ml,2x1ml,1x10ml 11202H APO A-1/APO B Calibrator 3x2ml Sentinel Clinical Chemistry - A/B


Catalogue_WEB_WoP_Jun16
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